Table 1. Mouse cone flash response parameters.
| Genotype | n | rmax (pA) | I1/2 (P*) | Time to peak (ms) | τrec (ms) | A (s−2) | Rin (MΩ) | Cm (pF) |
|---|---|---|---|---|---|---|---|---|
| C57BL/6J cones | 13 | 30 ± 2.0 | 470 ± 89 | 41 ± 1.9 | 200 ± 18 | 5.3 ± 0.4 | 850 ± 120 | 7.5 ± 0.5 |
| 24 ± 0.6 | 155 ± 28 | |||||||
| C57BL/6J rods | 5 | 17 ± 1.6 | 14 ± 2.4 | 200 ± 17 | 130 ± 23 | 4.6 ± 0.3 | 4,000 ± 680 | 3.6 ± 0.3 |
| 140 ± 20 | 260 ± 59 | |||||||
| Gnat1−/− cones | 25 | 21 ± 0.9 | 940 ± 110 | 59 ± 3.2 | 28 ± 1.9 | 2.1 ± 0.2 | 1,500 ± 350 | 6.9 ± 0.6 |
| 33 ± 1.9 | 42 ± 1.9 | |||||||
| Cx36−/− cones | 30 | 26 ± 1.3 | 990 ± 93 | 79 ± 4.8 | 64 ± 8.5 | 1.1 ± 0.1 | 850 ± 130 | 7.5 ± 0.3 |
| 50 ± 1.9 | 61 ± 3.4 | |||||||
| Gnat1−/−;Rv−/− cones | 36 | 20 ± 0.9 | 1,100 ± 110 | 55 ± 4.6 | 33 ± 3.1 | 1.7 ± 0.1 | 770 ± 140 | 6.2 ± 0.3 |
| 30 ± 2.4 | 47 ± 2.2 | |||||||
| Gnat1−/−;Gcaps−/− cones | 30 | 14 ± 0.9 | 740 ± 120 | 79 ± 5.5 | 125 ± 28 | 1.8 ± 0.1 | 1,200 ± 310 | 6.6 ± 0.4 |
| 43 ± 2.4 | 98 ± 6.4 | |||||||
| Gnat1−/−;Rv−/; Gcaps−/−cones | 34 | 23 ± 1.4 | 550 ± 51 | 67 ± 2.4 | 94 ± 8.5 | 2.2 ± 0.1 | 660 ± 27 | 6.8 ± 0.2 |
| 42 ± 2.3 | 110 ± 7.3 |
For parameters that are dependent on light intensity, two values are reported corresponding to ∼25% (top) and 90% (bottom) of rmax. Values are means ± SEM. Statistical comparisons are given in the text.