Table 2. Mouse cone steady-light response parameters.
Genotype | n | rmax,pk (pA) | rmax,ss (pA) | I1/2,ss (P*/s) | Time to peak (ms) | τrec1 (ms) | τrec2 (s) | A1/A2 | Recovery (%) |
---|---|---|---|---|---|---|---|---|---|
Gnat1−/− cones | 9 | 21 ± 3.2 | 18 ± 2.5 | 250,000 ± 95,000 | 140 ± 17 | 105 ± 8 | 1.4 ± 0.34 | 1.5 ± 0.66 | 51 ± 3 |
Gnat1−/−;Rv−/− cones | 11 | 20 ± 1.5 | 17 ± 1.5 | 600,000 ± 175,000 | 110 ± 11 | 223 ± 64 | 1.3 ± 0.26 | 1.7 ± 0.70 | 41 ± 4 |
Gnat1−/−;Gcaps−/− cones | 10 | 19 ± 2.3 | 16 ± 1.8 | 68,000 ± 13,000 | 155 ± 15 | 330 ± 38 | 19 ± 3 | ||
Gnat1−/−;Rv−/−; Gcaps−/−cones | 9 | 24 ± 2.6 | 20 ± 2.7 | 63,000 ± 27,000 | 180 ± 11 | 490 ± 76 | 18 ± 4 |
Values are means ± SEM. Statistical comparisons are given in the text. I1/2,ss, sensitivity of steady-state current response; rmax,pk, peak current response, measured <200 ms after stimulus onset; rmax,ss, steady-state current response, averaged from the last 1 s of the brightest stimulus.