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. 2019 Sep 26;151(11):1300–1318. doi: 10.1085/jgp.201912390

Table 1. Figure 2 electrophysiological measurements segregated by sex.

Measure WT NaVβ4−/− WT NaVβ4Δp/Δp
M (n = 4) F (n = 2) M (n = 2) F (n = 6) M (n = 6) F (n = 3) M (n = 6) F (n = 3)
Gmax (nS) 78.5 ± 8.1 107.2 ± 3 61.4 ± 0.18 61.5 ± 8.1 74.8 ± 8.5 44.7 ± 11 61.8 ± 5.8 76.1 ± 1.2
V1/2 activation (mV) −34 ± 2.6 −42 ± 6.3 −37.5 ± 3.5 −35.3 ± 0.6 −39.1 ± 3.2 −37.1 ± 1.9 −37.2 ± 1.3 −40.3 ± 0.6
k activation (mV) 5.97 ± 0.21 6.56 ± 1.53 6.13 ± 0.99 5.90 ± 0.39 4.65 ± 0.51 5.54 ± 0.53 4.59 ± 0.16 5.05 ± 0.58
V1/2 inactivation (mV) −59.7 ± 1.71 −62.3 ± 2.1 −58.1 ± 0.83 −62.5 ± 1.6 −61.3 ± 1.2 −60.6 ± 0.1 −60.6 ± 0.96 −60.7 ± 1.1
k inactivation (mV) 6.13 ± 0.26 5.72 ± 0.01 5.57 ± 0.05 6.12 ± 0.17 5.65 ± 0.21 5.62 ± 0.81 6.03 ± 0.22 6 ± 0.05
Irsg rise (ms) 7.36 ± 0.55 6.07 ± 0.22 6.25 ± 1.36 6.29 ± 0.43 5.08 ± 0.37 6.67 ± 1.58 5.99 ± 0.43 8.09 ± 0.96
Irsg decay τ (ms) 27.3 ± 2.1 26.5 ± 3.9 25.8 ± 0.95 27.6 ± 0.99 22.9 ± 0.53 23.4 ± 0.88 26.1 ± 3.6 28.5 ± 2
Relative rsg (%) 2.67 ± 0.28 2.3 ± 0.06 2.88 ± 0.39 2.28 ± 0.49 2.3 ± 0.19 2.69 ± 0.08 2.58 ± 0.26 2.7 ± 0.13