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. Author manuscript; available in PMC: 2021 Jan 13.
Published in final edited form as: Behav Brain Res. 2019 Sep 16;377:112236. doi: 10.1016/j.bbr.2019.112236

Figure 1: Amygdala lesions alter CO2-evoked behaviors.

Figure 1:

A) Diagram [58] showing size and location of the largest (red) and smallest (blue) amygdala lesions. B) Amygdala lesions reduce CO2-evoked freezing. ANOVA revealed an interaction between CO2 concentration and lesion status (F(2,57) = 7.382, p = 0.0014, n = 15, 7, 18, 10, 6, 6). Planned contrast testing revealed that amygdala lesions reduce freezing to both 10% (***p = 0.0004) and 20% CO2 (*p = 0.0481). C) Amygdala lesions elicit 10% CO2-evoked jumping. ANOVA revealed an interaction between CO2 concentration and lesion status (F(2,57) = 5.248, p = 0.0081. Planned contrast testing revealed that mice with amygdala lesions exhibit increased jumping in response to 10% (***p < 0.0001) but not 20% (p = 0.9709) CO2, and that sham controls jumped more in response to 20% CO2 than 10% CO2 (p = 0.0066).