Table 2. Assessment of the quality and risk of bias of 19 selected systematic reviews of treatments for anxiety disorders, in accordance with the A MeaSurement Tool to Assess systematic Reviews (AMSTAR 2.0) and Risk Of Bias In Systematic reviews (ROBIS).
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | AMSTAR | ROBIS | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Author | PICO | Protocol | Study selection | Literature search | Selection in duplicate | Extraction in duplicate | Excluded studies | Included studies | Individual risk of bias | Funding of studies | Appropriate meta-analysis | Impact of risk of bias | Interpreting/ discussing results | Discussion of heterogeneity | Publication bias | Conflict of interest | Quality | Risk of bias |
Nonbiological or psychological treatments | ||||||||||||||||||
Mayo-Wilson, 2013 (25) | High | Low | ||||||||||||||||
Jayakody, 2014 (22) | NA | NA | NA | Low | Uncertain | |||||||||||||
Arnberg, 2014 (26) | Moderate | Low | ||||||||||||||||
Abbass, 2014 (27) | High | Low | ||||||||||||||||
Norton, 2015 (23) | NA | NA | NA | Moderate | Uncertain | |||||||||||||
Olthuis, 2015 (28) | High | Low | ||||||||||||||||
Wu, 2015 (30) | High | Low | ||||||||||||||||
Newby, 2015 (29) | RCTNRCT | Low | Uncertain | |||||||||||||||
Piccirillo, 2016 (24) | NA | NA | NA | Critical low | High | |||||||||||||
Stubbs, 2017 (31) | Moderate | Low | ||||||||||||||||
Cramer, 2018 (32) | Low | Uncertain | ||||||||||||||||
Biological or pharmacological treatments | ||||||||||||||||||
Li, 2014 (33) | High | Low | ||||||||||||||||
Patterson, 2016 (34) | Low | Uncertain | ||||||||||||||||
Williams, 2017 (35) | High | Low | ||||||||||||||||
Sugarman, 2017 (36) | Critical low | High | ||||||||||||||||
Yee, 2018 (37) | Critical low | High | ||||||||||||||||
Multimodal combinedtreatment comparisons | ||||||||||||||||||
Bandelow, 2015 (15) | Low | Uncertain | ||||||||||||||||
Ho, 2016 (38) | Low | Uncertain | ||||||||||||||||
Bandelow, 2018 (14) | Low | Uncertain |
Footnotes:
Yes
No
Partial Yes
NA: not applicable - no meta-analysis.
RCT/NRCT: randomized controlled trials/nonrandomized controlled trials.