Table 2.

Meta-analysis of 9 different expressed aging related genes in COPD group

Gene symbol	Effect size (SMD)	95% CI	p-value
TGFB1	− 3.85	[−6.38, − 1.31]	0.003
TP53	−2.66	[−4.44, − 0.88]	0.003
MMP2	−1.76	[−2.96, −0.56]	0.004
AREG	−3.02	[−5.25, −0.80]	0.008
E2F1	−1.4	[−2.51, −0.30]	0.01
HDAC1	−3.3	[−5.94, −0.67]	0.01
NUF2	−2.62	[−4.72, −0.52]	0.01
FOXO3	−1.84	[−3.34, −0.34]	0.02
ATG3	−2.6	[−4.89, −0.30]	0.03

A p value < 0.05 was considered statistically significant