Table 2.

This table shows the 20 genes that are in the set of conserved cisplatin-responsive gene set, and how those genes are up- and down-expressed in each of four Lehmann-identified TNBC subtypes. ‘UP’ indicates the gene is over-expressed and ‘DOWN’ indicates the gene is under-expressed. The ‘LAR’ or ‘M’ column indicates that the gene is differentially expressed in one of the two cisplatin-resistant subtypes compared with the BL1 or BL2 sensitive subtypes. The ‘Cell Death’ column indicates if the gene has been associated with a Gene Ontology term describing an aspect of cell death

Gene Symbol	Gene Name	BL1	BL2	M	LAR	Resistant	Death
ABCC2	ATP binding cassette subfamily C member 2				UP	*
ADM	adrenomedullin		UP	UP			*
AKT1	AKT serine/threonine kinase 1				UP	*	*
BCL2	BCL2 apoptosis regulator	DOWN					*
BCL2L1	BCL2 like 1				UP	*	*
CASP8	caspase 8			DOWN	UP	*	*
CAV1	caveolin 1		UP				*
CLU	clusterin	DOWN			UP	*	*
FAS	Fas cell surface death receptor			DOWN		*	*
FOS	Fos proto-oncogene, AP-1 transcription factor subunit	DOWN					*
GSR	glutathione-disulfide reductase				UP	*
GJA1	gap junction protein alpha 1	DOWN	UP	UP			*
HSPB1	heat shock protein family B (small) member 1		UP		UP		*
MSH2	mutS homolog 2	UP			DOWN	*	*
NOX4	NADPH oxidase 4	DOWN		UP		*	*
NQO1	NAD(P)H quinone dehydrogenase 1				UP	*	*
PTK2	protein tyrosine kinase 2	UP					*
TUBA1A	tubulin alpha 1a			UP	DOWN	*
VCAM1	vascular cell adhesion molecule 1			DOWN		*
VIM	vimentin			UP	DOWN	*