Table 2.
List of human virulence-facilitating genes
| Gene | Product | Function | Reference |
|---|---|---|---|
| cblA | cable pilus | Promotes adhesion to host epithelial cells | [55] |
| adhA | 22 kDa-adhesin | [56] | |
| esmR | BCESM | Burkholderia cenocepacia epidemic strain marker region | [53, 57] |
| amiI | |||
| cciI | |||
| cciR | |||
| opcI | |||
| kdgR | transcriptional regulator of metabolic genes | Can improve virulence | [58–60] |
| baiE | bile acid 7-alpha dehydratase | Putatively involved in a steroid degradation pathway Allows viability within host macrophage | [61–65] |
| tauX | taurine dehydrogenase | ||
| xsc | sulfoacetaldehyde acetyltransferase | ||
| telA | tellurite resistance protein | tellurite resistance | [66, 67] |
| terCEF | integral membrane protein | ||
| narIJHG | nitrate reductase gamma subunit | anaerobic metabolism through nitrate reduction | [68] |
| narL | DNA-binding response regulator | ||
| narX | Nitrate/nitrite sensor protein | ||
| lxa | low oxygen activated locus | maintains cell viability after oxygen depletion | [69] |