Figure 1.
DAXX expression decreased in colorectal tumor and was correlated with CD24 expression. These protein levels were evaluated by WB in 106 matched pairs of colorectal cancer (CRC) and nontumoral- surrounding tissues. Spearman correlation analysis revealed that the correlation between (A) CD24 expression and CEA level was nonsignificant (rho = 0.118, p = 0.1028), (B) DAXX expression and CD24 expression was significant (rho = 0.360, p < 0.001), (C) DAXX expression and β-catenin expression was significant (rho = −0.276, p < 0.005), (D) DAXX expression and CD24 expression was significant (rho = 0.265, p = 0.0658) in the CEA screening-negative subgroup, and (E) DAXX expression and CD24 expression was significant (rho = 0.461, p < 0.005) when evaluated in the CEA screening-positive subgroup. β-actin was the internal control.