Table 2.

Small molecule modulators of CMA activity.

Compounds	Target	Effect on CMA	Refs
Cycloheximide	Protein synthesis inhibitor	Inhibition	[99]
Anisomycin	Protein synthesis inhibitor	Inhibition	[99]
SB230580	P38 MAPK inhibitor	Inhibition	[99]
Geldanamycin	HSP90 inhibitor	Activation	[99]
17-AAG/DCA	HSP90 inhibitor + PDK1 inhibitor	Activation	[100]
6-aminonicotinamide	G6PDH inhibitor	Activation	[99]
synthetic ATRA derivatives	RAR-alpha inhibitor	Activation	[101]
torin	TORC2 inhibitor	Activation	[24]
TAK165/AC220	MA inhibitor + FLT3 Inhibitor	Activation	[91]
Spautin/AC220	MA inhibitor + FLT3 Inhibitor	Activation	[32]