Table 1.
Randomized clinical trials of SMS interventions for TB: Study design.
| Trial ID | Trial registry | Population | Study design | Location | Sample size | SMS intervention | Arm 2 | Arm 3 | Control |
|---|---|---|---|---|---|---|---|---|---|
| Mohammed 2016 [42] | NCT01690754 | Newly diagnosed TB | Individual RCT, open label | Pakistan | 2207 | Two-way SMS reminders | – | – | DOT |
| Liu 2015 [47] | ISRCTN46846388 | Newly diagnosed TB | Cluster RCT | China | 4292 | Two-way SMS reminders | Medication monitor | SMS reminder + medication monitor | Self-administered therapy, family supervision, or DOT |
| TB-SMS Cameroon [48], [49] | PACTR201307000583416 | Active TB | Individual RCT with single blind of health care providers | Cameroon | 279 | One-way SMS reminders | – | – | DOT |
| Belknap 2017 [50] | NCT01582711 | Latent TB | Individual RCT, blinding info NA | US, Spain, Hong Kong, and South Africa | 964 | Weekly SMS reminders + self-administered therapy | Self-administered therapy | – | DOT (monthly) |
| Fang 2017 [51] | – | Active TB | Cluster RCT, blinding info NA | China | 350 | One-way SMS reminders | – | – | DOT |
| WelTel LTBI [53], [75] | NCT01549457 | Latent TB | Individual RCT, open label | Canada | 350 | Two-way SMS check-ins | – | – | Self-administered therapy, |