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. 2019 Oct 24;10:2511. doi: 10.3389/fimmu.2019.02511

Table 3.

Association of continuous natural log transformed urinary properdin and urinary sC5b-9 with graft failure in renal transplant recipients.

Model Ln properdin Ln sC5b-9
HR (95% CI) P-value HR (95% CI) P-value
Univariate 1.36 (1.21–1.52) <0.001 1.76 (1.51–2.06) <0.001
Model 1 1.26 (1.11–1.43) <0.001 1.61 (1.35–1.91) <0.001
Model 2 1.25 (1.10–1.42) 0.001 1.61 (1.36–1.92) <0.001
Model 3 1.25 (1.10–1.42) 0.001 1.63 (1.36–1.96) <0.001
Model 4 1.12 (1.02–1.28) 0.008 1.34 (1.10–1.63) 0.004

Model 1, adjustment for age, sex, primary renal disease, time since transplantation at inclusion, eGFR, HLA mismatches, and donor type; model 2, model 1 + adjustment for hs-CRP; model 3, model 2 + adjustment for systolic blood pressure, and smoking; model 4, model 3 + adjustment for proteinuria.