Table 1.
Demographic and Biological Characteristics of Subjects
| Control-w/oELA (n = 13) |
Control-wELA (n = 13) |
MDDSui-w/oELA (n = 13) |
MDDSui-w/ELA (n = 13) |
Statistics |
||
|---|---|---|---|---|---|---|
| Variables | Mean (SD) [Min, Max] | Mean (SD) [Min, Max] | Mean (SD) [Min, Max] | Mean (SD) [Min, Max] | F3,51 | ANOVA p Value |
| Age, Years | 38.5 (14.5) [14-58] | 36.6 (18.5) [18-66] | 41.5 (10.9) [25-61] | 36.3 (20.1) [13-65] | 0.267 | .849 |
| PMI | 15.3 (5.1) [6.00-22.0] | 14.2 (4.0) [8.00-21.00] | 14.7 (6.8) [3.00-24.00] | 17.5 (6.4) [3.00-27.00] | 2.095 | .113 |
| Brain pH | 6.4 (0.4) [5.68-6.87] | 6.5 (0.3) [5.93-6.84] | 6.5 (0.3) [6.00-6.93] | 6.4 (0.3) [6.20-6.77] | 0.826 | .488 |
| Brain Weight, g | 1399.2 (124.6) [1213-1600] | 1321.2 (188.6) [1000-1450] | 1369.5 (211.5) [1120-1550] | 1475.0 (91.9) [1410-1540] | 0.573 | .640 |
| BMI | 26.3 (5.5) [19.57-35.70] | 25.5 (6.6) [19.98-42.66] | 24.5 (4.6) [20.36-31.35] | 22.2 (2.7) [19.53-26.66] | 0.608 | .617 |
| n (%) | n (%) | n (%) | n (%) | χ2 Test | χ2 p Value | |
| Sex | 3.611 | .307 | ||||
| Male | 7 (53.8) | 11 (84.6) | 8 (61.5) | 10 (76.9) | ||
| Female | 6 (46.2) | 2 (15.4) | 5 (38.5) | 3 (23.1) | ||
| Ethnicity | 10.292 | .113 | ||||
| Caucasian descent | 12 (92.3) | 8 (61.5) | 12 (92.3) | 10 (76.9) | ||
| African descent | 1 (7.7) | 3 (23.1) | 0 | 1 (7.7) | ||
| Hispanic descent | 0 | 2 (15.4) | 1 (7.7) | 2 (15.4) | ||
| Cause of Death | ||||||
| Blunt trauma | 8 | 2 | – | – | ||
| Cardiovascular | 3 | 9 | – | – | ||
| Respiratory | 2 | – | – | – | ||
| Hemorrhage | – | 2 | – | – | ||
| Hanging/drowning | – | – | 9 | 6 | ||
| Overdose/poisoning | – | – | 3 | 4 | ||
| Immolation | – | – | 1 | – | ||
| Fall from height | – | – | – | 3 | ||
| Brain/Blood Toxicology | ||||||
| ACE inhibitors | 0 | 1 | 1 | 1 | ||
| Lidocaine/opioids | 4 | 2 | 1 | 0 | ||
| None | 9 | 10 | 11 | 12 | ||
ACE, angiotensin-converting enzyme; ANOVA, analysis of variance; BMI, body mass index; Control-wELA, resilient control subjects with ELA; Control-w/oELA, control subjects without ELA; ELA, early life adversity; MDD, major depressive disorder; MDDSui-wELA, subjects with MDD who died by suicide with ELA; MDDSui-w/oELA, subjects with MDD who died by suicide without ELA; PMI, postmortem interval.