Table 2.
Subject Sample Clinical Features
| Control-w/oELA (a) (n = 13) |
Control-wELA (b) (n = 13) |
MDDSui-w/oELA (c) (n = 13) |
MDDSui-w/ELA (d) (n = 13) |
Statistics (Post Hoc Comparison of a, b, c, d) |
|||
|---|---|---|---|---|---|---|---|
| Variables | Mean (SD) [Min, Max] | Mean (SD) [Min, Max] | Mean (SD) [Min, Max] | Mean (SD) [Min, Max] | F3,51 | ANOVA p Value | Tukey Post Hoc Test |
| Age of MDD Onset, Years | – | – | 35.7 (14.2) [17-59] | 41.1 (18.1) [17-64] | 0.531 | .476 | |
| Duration of MDD, Years | – | – | 6.1 (7.2) [0.3-20.00] | 3.6 (4.3) [0.3-11.00] | 0.780 | .389 | |
| Number of MDEs in Lifetime | – | – | 2.0 (1.5) [1-5] | 1.2 (0.4) [1-2] | 1.726 | .212 | |
| GAS Score | 87.7 (7.1) [76-100] | 85.6 (9.1) [65-100] | 39.0 (16.1) [1-55] | 41.8 (25.7) [1-75] | 24.573 | .000 | a>c, a>d, b>c, b>d: p < .001 |
| BGAS Score | 12.5 (3.6) [10-21] | 13.7 (6.7) [10-30] | 12.3 (2.9) [10-18] | 14.2 (4.7) [10-23] | 0.433 | .731 | |
| SPRS Total Score | 9.8 (3.2) [6.00-17.00] | 9.0 (2.6) [6.00-13.00] | 12.9 (2.8) [10.00-17.00] | 14.8 (3.7) [10.00-21.00] | 7.187 | .001 | a>d: p = .005 b>c: p = .031 b>d: p = .002 |
| SPRS Axis IV Impact Score | 1.8 (1.0) [1.00-4.00] | 2.2 (1.0) [1.00-4.00] | 4.1 (1.3) [2.00-6.00] | 4.3 (1.0) [2.00-5.00] | 14.108 | .000 | a>c, a>d: p < .001 b>c, b>d: p = .002 |
| n (%) | n (%) | n (%) | n (%) | χ2 Test | χ2 p Value | ||
| SPRS Axis IV Impact Score | 29.497 | .014 | |||||
| None-minimal (1-2) | 10 (76.9) | 8 (61.5) | 2 (15.4) | 2 (15.4) | |||
| Mild-moderate (3-4) | 3 (23.1) | 5 (38.5) | 4 (30.8) | 3 (23.1) | |||
| Severe-extreme (5-6) | 0 | 0 | 7 (53.8) | 8 (61.5) | |||
ANOVA, analysis of variance; BGAS, Brown–Goodwin Aggression Scale; Control-wELA, resilient control subjects with ELA; Control-w/oELA, control subjects without ELA; ELA, early life adversity; GAS, Global Assessment Scale; MDD, major depressive disorder; MDDSui-wELA, subjects with MDD who died by suicide with ELA; MDDSui-w/oELA, subjects with MDD who died by suicide without ELA; MDE, major depressive episode; SPRS, St. Paul–Ramsey Scale.