Table 1.
ABC Transporter | Related Disease or Condition |
---|---|
ABCC7 (CFTR) | cystic fibrosis (CF), male infertility |
ABCC6 (MRP6) | pseudoxanthoma elasticum (PXE) |
ABCB11 (BSEP) | type II progressive familial intrahepatic cholestasis (PFIC-II), drug toxicity |
ABCB4 (MDR3) | type III progressive familial intrahepatic cholestasis (PFIC-III), drug toxicity |
ABCG2 (BCRP/MXR) | gout, cancer multidrug resistance, drug toxicity |