Figure 3.

Structural organisation of nucleoporins in the NPC: Nups are organised into various subcomplexes, which here are shown in different coloured boxes. The location of Nups is marked on the left half of the NPC framework—the central transport channel/Nup62 subcomplex is shown in green; adapter ring/inner ring complex is in brick red; transmembrane Nups are in purple; Y-complexes are shown in orange; cytoplasmic ring Nups are in pink; Nups forming the cytoplasmic filaments are in light blue; nuclear basket is shown in teal color. The Nups highlighted in red are the ones identified as essential during the HIV-1 infection. The FG-Nups are underlined.