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. 2019 Oct 21;39(10):BSR20191549. doi: 10.1042/BSR20191549

Table 3. Stratified analyses between rs1799750 polymorphisms and the risk of RCT.

Variable rs1799750 (case/control) 1G/2G vs. 1G/1G 2G/2G vs. 1G/1G 2G/2G vs. 1G/1G +CT 2G/2G +1G/2G vs. 1G/1G
1G/1G 1G/2G 2G/2G
Sex
  Male 17/22 43/34 21/13 1.64 (0.75–3.56); 0.214 2.09 (0.82–5.34); 0.123 1.51 (0.69–3.30); 0.303 1.76 (0.84–3.68); 0.132
  Female 20/28 31/39 17/12 1.11 (0.53–2.34); 0.778 1.98 (0.78–5.06); 0.151 1.86 (0.82–4.24); 0.140 1.32 (0.66–2.64); 0.437
Smoking
  Yes 17/21 36/18 17/8 2.47 (1.05–5.80); 0.038 2.63 (0.91–7.55); 0.073 1.56 (0.61–3.99); 0.350 2.52 (1.14–5.57); 0.023
  No 20/29 38/55 21/17 1.00 (0.50–2.03); 0.996 1.79 (0.76–4.22); 0.182 1.79 (0.87–3.68); 0.114 1.19 (0.61–2.31); 0.612
Alcohol
  Yes 20/22 43/26 20/5 1.82 (0.84–3.96); 0.131 4.40 (1.39–13.92); 0.012 3.05 (1.07–8.70); 0.037 2.24 (1.06–4.70); 0.034
  No 17/28 31/47 18/20 1.09 (0.51–2.31); 0.830 1.48 (0.62–3.56); 0.379 1.41 (0.68–2.93); 0.362 1.21 (0.59–2.44); 0.606
Age (years)
  <60 31/31 52/49 27/16 1.06 (0.56–2.00); 0.854 1.69 (0.76–3.73); 0.196 1.63 (0.82–3.24); 0.168 1.22 (0.67–2.21); 0.521
  ≥60 6/19 22/24 11/9 2.90 (0.98–8.59); 0.054 3.87 (1.09–13.81); 0.037 1.88 (0.69–5.11); 0.218 3.17 (1.12–8.93); 0.029
Hypertension
  Yes 9/13 27/22 7/5 1.77 (0.64–4.92); 0.271 2.02 (0.49–8.43); 0.334 1.36 (0.40–4.70); 0.626 1.82 (0.68–4.89); 0.236
  No 28/37 47/51 31/20 1.22 (0.65–2.29); 0.541 2.05 (0.97–4.32); 0.060 1.82 (0.96–3.45); 0.067 1.45 (0.81–2.61); 0.213
Diabetes
  Yes 10/6 23/16 6/1 0.86 (0.26-2.85); 0.809 3.60 (0.35-37.60); 0.285 4.00 (0.45-35.54); 0.214 1.02 (0.32-3.32); 0.969
  No 27/44 51/57 32/24 1.46 (0.79-2.68); 0.226 2.17 (1.06-4.44); 0.031 1.73 (0.94-3.17); 0.077 1.67 (0.95-2.95); 0.077
Thyroid disease
  Yes 1/2 6/9 4/1 1.33 (0.10-18.19); 0.829 8.00 (0.31-206.36); 0.210 6.29 (0.58-68.42); 0.131 2.00 (0.16-25.75); 0.595
  No 35/48 68/64 34/24 1.42 (0.82–2.46); 0.215 1.89 (0.96–3.72); 0.066 1.53 (0.85–2.74); 0.158 1.55 (0.92–2.59); 0.099

Bold values are statistically significant (P<0.05).