Table 3. Stratified analyses between rs1799750 polymorphisms and the risk of RCT.
| Variable | rs1799750 (case/control) | 1G/2G vs. 1G/1G | 2G/2G vs. 1G/1G | 2G/2G vs. 1G/1G +CT | 2G/2G +1G/2G vs. 1G/1G | ||
|---|---|---|---|---|---|---|---|
| 1G/1G | 1G/2G | 2G/2G | |||||
| Sex | |||||||
| Male | 17/22 | 43/34 | 21/13 | 1.64 (0.75–3.56); 0.214 | 2.09 (0.82–5.34); 0.123 | 1.51 (0.69–3.30); 0.303 | 1.76 (0.84–3.68); 0.132 |
| Female | 20/28 | 31/39 | 17/12 | 1.11 (0.53–2.34); 0.778 | 1.98 (0.78–5.06); 0.151 | 1.86 (0.82–4.24); 0.140 | 1.32 (0.66–2.64); 0.437 |
| Smoking | |||||||
| Yes | 17/21 | 36/18 | 17/8 | 2.47 (1.05–5.80); 0.038 | 2.63 (0.91–7.55); 0.073 | 1.56 (0.61–3.99); 0.350 | 2.52 (1.14–5.57); 0.023 |
| No | 20/29 | 38/55 | 21/17 | 1.00 (0.50–2.03); 0.996 | 1.79 (0.76–4.22); 0.182 | 1.79 (0.87–3.68); 0.114 | 1.19 (0.61–2.31); 0.612 |
| Alcohol | |||||||
| Yes | 20/22 | 43/26 | 20/5 | 1.82 (0.84–3.96); 0.131 | 4.40 (1.39–13.92); 0.012 | 3.05 (1.07–8.70); 0.037 | 2.24 (1.06–4.70); 0.034 |
| No | 17/28 | 31/47 | 18/20 | 1.09 (0.51–2.31); 0.830 | 1.48 (0.62–3.56); 0.379 | 1.41 (0.68–2.93); 0.362 | 1.21 (0.59–2.44); 0.606 |
| Age (years) | |||||||
| <60 | 31/31 | 52/49 | 27/16 | 1.06 (0.56–2.00); 0.854 | 1.69 (0.76–3.73); 0.196 | 1.63 (0.82–3.24); 0.168 | 1.22 (0.67–2.21); 0.521 |
| ≥60 | 6/19 | 22/24 | 11/9 | 2.90 (0.98–8.59); 0.054 | 3.87 (1.09–13.81); 0.037 | 1.88 (0.69–5.11); 0.218 | 3.17 (1.12–8.93); 0.029 |
| Hypertension | |||||||
| Yes | 9/13 | 27/22 | 7/5 | 1.77 (0.64–4.92); 0.271 | 2.02 (0.49–8.43); 0.334 | 1.36 (0.40–4.70); 0.626 | 1.82 (0.68–4.89); 0.236 |
| No | 28/37 | 47/51 | 31/20 | 1.22 (0.65–2.29); 0.541 | 2.05 (0.97–4.32); 0.060 | 1.82 (0.96–3.45); 0.067 | 1.45 (0.81–2.61); 0.213 |
| Diabetes | |||||||
| Yes | 10/6 | 23/16 | 6/1 | 0.86 (0.26-2.85); 0.809 | 3.60 (0.35-37.60); 0.285 | 4.00 (0.45-35.54); 0.214 | 1.02 (0.32-3.32); 0.969 |
| No | 27/44 | 51/57 | 32/24 | 1.46 (0.79-2.68); 0.226 | 2.17 (1.06-4.44); 0.031 | 1.73 (0.94-3.17); 0.077 | 1.67 (0.95-2.95); 0.077 |
| Thyroid disease | |||||||
| Yes | 1/2 | 6/9 | 4/1 | 1.33 (0.10-18.19); 0.829 | 8.00 (0.31-206.36); 0.210 | 6.29 (0.58-68.42); 0.131 | 2.00 (0.16-25.75); 0.595 |
| No | 35/48 | 68/64 | 34/24 | 1.42 (0.82–2.46); 0.215 | 1.89 (0.96–3.72); 0.066 | 1.53 (0.85–2.74); 0.158 | 1.55 (0.92–2.59); 0.099 |
Bold values are statistically significant (P<0.05).