Table 2.
Echocardiographic parameters for sacubitril/valsartan and angiotensin receptor blocker users.
| Variables | LCZ696 n = 22 |
ARB n = 59 |
P value |
|---|---|---|---|
| LAD, mm | 38.814 ± 2.910 | 40.244 ± 3.960 | 0.127 |
| LAVmax, ml | 48.713 ± 11.652 | 52.630 ± 13.926 | 0.244 |
| LA peak systolic strain, % | 37.536 ± 11.679 | 30.727 ± 11.892 | 0.024 |
| LVDd, mm | 50.075 ± 5.460 | 49.468 ± 5.950 | 0.677 |
| LVEF, % | 53.163 ± 6.456 | 56.558 ± 7.095 | 0.053 |
| E:e’ ratio | 11.040 ± 4.404 | 12.420 ± 4.327 | 0.208 |
| LAAeV, cm/s | 46.459 ± 18.250 | 31.481 ± 16.363 | 0.036 |
| LAAEF, % | 37.050 ± 14.289 | 29.413 ± 13.215 | 0.026 |
| SEC, % | 40.9% | 66.1% | 0.040 |
| LAAT, % | 18.2% | 22.0% | 0.705 |
Data are mean ± SD unless indicated. LAD, left atrial dimension; LAVmax, maximal left atrial volume; LVDd, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; E,e’ ratio, the ratio of the early transmitral flow velocity and the early mitral annular velocity; LAAeV, left atrial appendage emptying flow velocity; LAAEF, left atrial appendage ejection fraction; SEC, spontaneous echocardiographic contrast; LAAT, left atrial appendage thrombus.