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. 2019 Oct 29;10:1223. doi: 10.3389/fphar.2019.01223

Table 2.

Phytochemical constituents of Gymnema sylvestre.

Constituents Classification Chemical Structure References
Triterpene saponins Gymnemic acids-acylated (tiglolyl,
methylbutyroyl) derivatives of
deacylgymnemic acid (DAGA) which is a
3-O-β-glucouronide of gymnemagenin (3β,
16β, 21β, 22α, 23,
28-hexahydroxy-Olean-12-ene).
graphic file with name fphar-10-01223-g003.jpg (Liu et al., 1992)
Oleanane Saponins Gymnemic acids and gymnemasaponins graphic file with name fphar-10-01223-g004.jpg (Ye et al., 2000)
Gymnemanol 3,β-16,β-22,
α-23-28-pentahydroxyolean-12-ene
graphic file with name fphar-10-01223-g005.jpg (Sahu et al., 1996)
Dammarene Saponins Gymnemoside A, B, C,D,E,F Inline graphic
Inline graphic
(Yoshikawa et al., 1997; Yoshikawa et al., 1998)
Gymmestrogenin Pentahydroxytriterpene graphic file with name fphar-10-01223-g008.jpg (Yoshikawa et al., 1998)
Gurmarin A 35-Amino acid peptide with a molecular weight of 4209 <1Glu- Gln- Cys- Val- 5Lys- Lys- Asp- Glu- Leu- 10Cys- Ile- Pro-Tyr- Tyr- 15Leu- Asp- Cys- Cys- Glu- 20Pro- Leu- Glu- Cys- Lys-25Lys- Val- Asn- Trp- Trp- 30Asp- His- Lys- Cys- Ile- 35Gly>.
(Glu = pyroglutamic-acid)
(Imoto et al., 1991)
Triterpenoid saponins
Gymnemasin A
Gymnemasin B
Gymnemasin C
Gymnemasin D
3-O [β-D-glucopyranosyl
(1-3)-β-D-glucopyranosyl]-22-O-tiglyol gymnemanol
3-O-[β-D-glucopyranosyl-(1-3)-β-D-glucuro- nopyranosyl]-
Gymnemanol
3-O-β-D-glucuronopyranosyl-22-O-tigloyl- gymnemanol
3-O-β-D-glucopyranosyl-gymnemanol
Inline graphic
Inline graphic
(J-GLOBAL-Japan Science and Technology Agency, n.d.a; J-GLOBAL-Japan Science and Technology Agency, n.d.b; J-GLOBAL-Japan Science and Technology Agency, n.d.c; J-GLOBAL-Japan Science and Technology Agency, n.d.d)
Flavonol glycoside Kaempferol 3-O-β-D-glucopyranosyl-(1-4)-α- L-rhamnopyranosyl-(1-6)- β-D-galactopyranoside graphic file with name fphar-10-01223-g011.jpg (Liu et al., 2004)
Sterols Stigmasterol graphic file with name fphar-10-01223-g012.jpg (Potawale et al., 2008)
Lupeol graphic file with name fphar-10-01223-g013.jpg (Sinsheimer et al., 1970)
d-Quercitol graphic file with name fphar-10-01223-g014.jpg (Potawale et al., 2008)
Parabin graphic file with name fphar-10-01223-g015.jpg (Sinsheimer et al., 1970)
Quercitol graphic file with name fphar-10-01223-g016.jpg (Tiwari et al., 2014).
Conduritol A graphic file with name fphar-10-01223-g017.jpg (Tiwari et al., 2014).