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. Author manuscript; available in PMC: 2019 Nov 5.
Published in final edited form as: J Cyst Fibros. 2018 Jun 22;18(1):127–134. doi: 10.1016/j.jcf.2018.05.013

Figure 1.

Figure 1.

An inactivating deletion in AGTR2 prevents aspects of pulmonary dysfunction in F508del CF mice. (A-E) Lung function and (F-J) distal airspace size were quantified in F508del CF mice, F508del CF mice with the genetic deletion of the AGTR2 gene (double knockout: AT/F508del), wild type C57bl/6 mice and AGTR2 knockout mice with wild type CFTR (AT KO). (G-J) Representative histologic images are displayed (size bars indicate 100 microns). Data are presented as means, with error bars denoting standard deviations. *P<0.05 compared to wild type; #P<0.05 compared to AT/F508del.