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. Author manuscript; available in PMC: 2019 Nov 5.
Published in final edited form as: J Cyst Fibros. 2018 Jun 22;18(1):127–134. doi: 10.1016/j.jcf.2018.05.013

Figure 2.

Figure 2.

An inactivating deletion in AGTR2 aspects of pulmonary dysfunction in R117H CF mice. (A-E) Lung function and (F-J) distal airspace size were also quantified in CF mice homozygous for the R117H CFTR mutation (R117H), and compared to CF mice with the genetic deletion of the AGTR2 gene (double knockout: AT/R117H), wild type C57bl/6 mice and AGTR2 knockout mice with wild type CFTR (AT KO). (G-J) Representative histologic images are displayed (size bars indicate 100 microns). Data are presented as means, with error bars denoting standard deviations. *P<0.05 compared to wild type; #P<0.05 compared to AT/F508del.