. Author manuscript; available in PMC: 2019 Nov 5.

Published in final edited form as: J Cyst Fibros. 2018 Jun 22;18(1):127–134. doi: 10.1016/j.jcf.2018.05.013

Table 2.

AGTR2 Risk Genotype Associates with Lower Spirometry Measurements in Individuals with CF

Pulmonary Function	Regression Coefficient	Bootstrap Standard Error	z-score	p-value	95% Confidence Interval
FEV ₁ (% predicted)	−7.1^*	1.01	7.01	<0.001	−5.09 – −9.04
FVC (% predicted)	−4.4^*	0.93	4.67	<0.001	−2.52 – −6.18
FEF _25-75 (% predicted)	−5.3^*	1.6	3.32	0.001	−2.18 – −8.47

= risk genotype (C/CC) worse than low-risk genotype (CT/T/TT)