Table 4.
Multivariable Predictive Model for all-cause death (Parsimonious Model)
| Predictor | HR (95% CI) | Chi-Square | P-value |
|---|---|---|---|
| Log of NT-pro-BNP | 1.86 (1.56 – 2.22) | 46.712 | <.001 |
| Sodium (mmol/L) | 0.91 (0.87 – 0.95) | 16.172 | <.001 |
| History of Ischemic Heart Disease | 2.01 (1.39 – 2.91) | 13.618 | <.001 |
| HF Duration (in years) | 1.05 (1.02 – 1.08) | 12.789 | <.001 |
| Diastolic Blood Pressure | 0.97 (0.96 – 0.99) | 12.398 | <.001 |
| Heart Rate | 1.02 (1.01 – 1.03) | 9.113 | 0.003 |
ǂ
Reported model selected from the following list of candidate predictors: NT-pro-BNP, diastolic blood pressure, sodium, heart rate, SpO2, depression handled with medication, third heart sound, 6-minute walk distance, heart failure duration, history of ischemic heart disease, age, and congestion score. Model was selected using backward selection with a significance level of 0.01 as the criterion for variable inclusion.
Uncorrected C-index: 0.765
Optimism-Corrected C-index: 0.757
Calibration (D’agostino, Nam test): p-value=0.68
Baseline Survival at 1 year [S0(1 year)]: 0.9414