. Author manuscript; available in PMC: 2020 Oct 1.

Published in final edited form as: Mult Scler Relat Disord. 2019 Aug 13;35:276–282. doi: 10.1016/j.msard.2019.08.014

Table 3:

Multivariate Regression Analysis of 25(OH)D₃ and Other Factors explaining MRI Feature

	WB-MTR			NABT-MTR			NAGM-MTR
Variable	b^*	β^**	P value	b^*	β^*	P value	b^*	β^*	P value
25(OH)D₃	0.0021	0.1524	0.01	0.0016	0.1098	0.08	0.0019	0.1377	0.03
Month	0.0091	0.1030	0.09	0.0092	0.1005	0.10	0.0039	0.0437	0.48
Latitude	−0.0072	−0.1044	0.09	−0.0076	−0.1052	0.09	−0.0030	−0.0421	0.50
Age	0.0042	0.1186	0.07	0.0013	0.0340	0.60	0.0008	0.0213	0.75
Sex	−0.0269	−0.0508	0.42	−0.0027	−0.0050	0.94	0.0239	0.0445	0.49
MS duration	−0.0003	−0.0112	0.86	−0.0007	−0.0254	0.70	0.0001	0.0060	0.93
SDMT	0.0043	0.2367	0.0001	0.0054	0.2900	<.0001	0.0032	0.1726	0.01
EDSS	-	-	-	-	-	-	−0.0072	−0.1021	0.12

Regression coefficient;

^**

Standardized coefficient

25[OH]D₃,25-hydroxyvitamin D₃; MS, Multiple Sclerosis; SDMT, Symbol Digit Modality Test; EDSS, Expanded Disability Status Scale; WB-MTR, whole brain magnetization transfer ratio; NABT-MTR, normal appearing brain tissue MTR; NAGM-MTR, normal appearing grey matter MTR