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. Author manuscript; available in PMC: 2020 Oct 25.
Published in final edited form as: Circ Res. 2019 Sep 24;125(10):e55–e70. doi: 10.1161/CIRCRESAHA.119.315786

Figure 7. CXCR4 expression on peripheral human B-1 cells associates with decreased plaque volume and protected plaque phenotype.

Figure 7.

(a) Plaque burden, stenosis, and composition were measured in human coronary arteries by intravascular ultrasound (IVUS) and virtual histology (VH). (b) Correlation plot of plaque burden with CXCR4 expression on B-1 cells (log(MFI CXCR4)) in 50 subjects. (c) Correlation plot of maximum stenosis with CXCR4 expression on B-1 cells (log(MFI CXCR4)) in 50 subjects. (d) Associations between CXCR4 expression on peripheral human B-1 cells and plaque burden, stenosis, plaque characteristics, or plasma cholesterol levels in 50 subjects. Data presented as correlation coefficient (r) and False Discovery Rate (FDR)-corrected statistical significance (p). *P<0.05 for FDR-corrected p-values.