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Average wound to background (W:B) contrast in terms of various tissue oxygenation parameters across weeks of treatment for VLU cases 3 and 4. The gray dashed line at a given week No. is when the VLU was diagnosed as healing by the clinician. The dotted gray line at week 18 in case 4 is when the VLU was diagnosed as healed by the clinician. Color images are available online.
