Table 2.

HRs and 95% CIs of WCC and its subtype relative to mortality

		N	All cause of death				Cancer death				CVD death
			Cases	HR (95% CI)			Cases	HR (95% CI)			Cases	HR (95% CI)
Total (N)		14 433	936				466				179
WCC	T1	5146	274	1			144	1			47	1
	T2	4514	252	1.01	0.85	1.21	122	0.90	0.70	1.15	53	1.20	0.81	1.79
	T3	4773	410	1.38	1.17	1.64	200	1.13	0.89	1.44	79	1.53	1.03	2.26
	P trend			<0.0001				0.282				0.031
Subtype of WCC
Lymphocytes	T1	4904	282	1			131	1			50	1
	T2	4985	306	1.08	0.92	1.28	160	1.18	0.93	1.49	61	1.19	0.81	1.74
	T3	4544	348	1.21	1.02	1.43	175	1.22	0.95	1.55	68	1.33	0.90	1.96
	P trend			0.025				0.119				0.154
Monocytes	T1	7387	455	1			225	1			76	1
	T2	2990	170	1.02	0.85	1.22	90	1.07	0.84	1.38	41	1.40	0.95	2.06
	T3	4056	311	1.22	1.04	1.43	151	1.15	0.92	1.44	62	1.33	0.92	1.92
	P trend			0.016				0.23				0.105
Neutrophils	T1	5008	269	1			138	1			48	1
	T2	4927	285	0.94	0.80	1.11	149	0.95	0.75	1.21	58	1.01	0.69	1.49
	T3	4498	382	1.29	1.09	1.52	179	1.07	0.84	1.36	73	1.35	0.92	1.99
	P trend			0.002				0.572				0.11
Eosinophils	T1	7911	484	1			245	1			83	1
	T2	3881	262	1.06	0.91	1.23	120	0.93	0.75	1.17	59	1.28	0.91	1.80
	T3	2641	190	1.25	1.05	1.49	101	1.25	0.98	1.59	37	1.30	0.87	1.95
	P trend			0.017				0.159				0.135
NLR*	T1	4831	275	1			146	1			48	1
	T2	4796	327	1.13	0.96	1.32	172	1.14	0.91	1.43	59	1.15	0.78	1.68
	T3	4805	334	1.09	0.93	1.29	148	0.91	0.72	1.15	72	1.34	0.92	1.94
	P trend			0.303				0.431				0.303

*Model adjusted by age and sex, alcohol consumption, physical activity, educational level, BMI, waist circumference and smoking intensity.

BMI, body mass index; CVD, cardiovascular disease; NLR, neutrophil-to-lymphocyte ratio; WCC, white cell count.