Table 2. The GC-IPL, total macula, and RNFL thickness measurements in the four groups.
| Severe AD (N = 9) | Mild to moderate AD (N = 7) | aMCI (N = 14) |
Control (N = 17) |
P-value ** |
|
|---|---|---|---|---|---|
| Average GC-IPL | 66.3 ± 10.0* | 76.2±10.5 | 82.7±8.0 | 82.5±5.6 | <0.001 |
| Total Macula | 244.7 ± 20.6* | 264.0±12.1* | 268.7±26.3 | 282.1±12.6 | 0.001 |
| Average RNFL | 77.06 ± 13.0* | 80.7±14.9* | 90.7±7.3 | 91.5±7.4 | 0.007 |
| Inferior RNFL | 98.3 ± 18.6* | 101.6±25.1* | 117.8±3.7 | 122.4± 13.6 | 0.004 |
| Superior RNFL | 93.7 ± 19.5* | 100.4±18.2 | 113.5±14.7 | 112.1±15.6 | 0.072 |
| Temporal RNFL | 56.1 ± 15.8 * | 61.4±8.6 | 65.8±10.3 | 66.9±10.6 | 0.114 |
| Nasal RNFL | 60.0 ± 6.3 | 58.0±12.2 | 65.8±8.0 | 63.5±9.2 | 0.476 |
The results represent the mean (μm) ± SD values,
* P<0.05 vs controls,
** ANCOVA (covariate: age), bold type indicates statistical significance.