Table 3. Multiple regression analysis with OCT measurements as dependent variables to assess contributions of the clinical disease severity adjusted by age.

Severity of dementia	OCT measurements (dependent variables)	Regression coefficient ß	Standard error	R2	p-value
GDS	GC-IPL	-5.3	1.62	0.352	<0.001*
	Total macula	-11.1	3.82	0.252	0.008*
	Average RNFL	-0.28			0.104
CDR	GC-IPL	-7.2	3.12	0.373	0.031*
	Total macula	-21.6	6.91	0.272	0.005*
	Average RNFL	-9.0		0.357	0.076
MMSE	GC-IPL	0.31			0.124
	Total macula	1.645	0.67	0.194	0.021*
	Average RNFL	1.12	0.35	0.273	0.004*

OCT: optical coherence tomography, MMSE: mini-mental status examination, CDR: clinical dementia rating, GDS: global deterioration scale,

* bold type indicates statistical significance.