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. 2018 Sep 20;24(7):394–399. doi: 10.1177/1753425918800555

Table 2.

Effects of matrine on apoptosis relative genes in A549 cells. Data are presented as mean ± SEM. The values having different superscript letters were significantly different with other groups (P < 0.05; n = 6).

Genes 0 μM Matrine 10 μM Matrine 50 μM Matrine 100 μM Matrine
p53 1.00 ± 0.08b 1.18 ± 0.13ab 1.33 ± 0.17ab 1.42 ± 0.22a
Casp3 1.00 ± 0.22a 0.87 ± 0.15a 0.91 ± 0.09a 0.52 ± 0.12b
Casp8 1.00 ± 0.24 0.89 ± 0.16 0.85 ± 0.17 0.79 ± 0.16
Casp9 1.00 ± 0.18 0.84 ± 0.16 0.92 ± 0.21 0.84 ± 0.18
Bcl-2 1.00 ± 0.08a 0.83 ± 0.11ab 0.77 ± 0.16b 0.43 ± 0.05b
Bax 1.00 ± 0.05b 1.37 ± 0.12a 1.40 ± 0.13a 1.68 ± 0.25a
Fas 1.00 ± 0.17 1.12 ± 0.12 1.27 ± 0.23 0.92 ± 0.02
Fas-L 1.00 ± 0.25 0.93 ± 0.21 1.28 ± 0.30 1.23 ± 0.26