Table 3.
Effects of matrine and CCL21 on apoptosis relative genes in A549 cells. Data are presented as mean ± SEM. The values having different superscript letters were significantly different with other groups (P < 0.05; n = 6).
| Genes | Control | Matrine | Matrine+CCL21 | CCL21 |
|---|---|---|---|---|
| p53 | 1.00 ± 0.06b | 1.55 ± 0.17a | 1.05 ± 0.17b | 0.71 ± 0.11c |
| Casp3 | 1.00 ± 0.12a | 0.58 ± 0.13b | 0.87 ± 0.22ab | 1.13 ± 0.09a |
| Casp8 | 1.00 ± 0.14 | 0.83 ± 0.12 | 0.94 ± 0.16 | 0.88 ± 0.11 |
| Casp9 | 1.00 ± 0.08 | 0.87 ± 0.15 | 1.14 ± 0.18 | 0.46 ± 0.26 |
| Bcl-2 | 1.00 ± 0.18b | 0.39 ± 0.07c | 0.73 ± 0.11b | 1.56 ± 0.08a |
| Bax | 1.00 ± 0.10b | 1.77 ± 0.22a | 1.34 ± 0.23ab | 0.62 ± 0.11c |
| Fas | 1.00 ± 0.07 | 1.12 ± 0.13 | 1.22 ± 0.02 | 1.21 ± 0.42 |
| Fas-L | 1.00 ± 0.05 | 1.19 ± 0.16 | 1.03 ± 0.26 | 1.29 ± 0.07 |