Table 2.
Characteristics of the population according to the presence of periodontitis risk haplotype.
| Whole population (n = 455) | Periodontitis risk haplotype in either chromosome (n = 387) | Other (n = 68) | ||
|---|---|---|---|---|
| Mean (SD) | P valuea | |||
| Age (yr) | 63.6 (9.2) | 63.5 (9.2) | 63.5 (8.6) | 0.996 |
| BMI (kg/m2) | 28.1 (5.1) | 28.1 (5.1) | 28.0 (4.8) | 0.793 |
| Number of teeth | 20.0 (8.8) | 19.5 (9.1) | 22.8 (6.2) | 0.001 |
| n (%) | P valueb | |||
| Sex (males) | 279 (61.3) | 236 (60.9) | 43 (63.2) | 0.597 |
| Ex or current smoker | 223 (49.0) | 193 (50.0) | 30 (44.1) | 0.559 |
| Dyslipidemia | 344 (75.6) | 295 (76.2) | 49 (72.0) | 0.495 |
| Diabetes | 106 (23.3) | 91 (23.5) | 15 (22.1) | 0.819 |
| Coronary artery disease | 317 (69.7) | 270 (70.0) | 47 (69.1) | 0.626 |
aT-Test for comparisons between the two groups.
bChi-square test. BMI, body mass index.Significant P values are highlighted in bold.
Analyses were performed in the Parogene population (n = 455) including patients with an indication to coronary artery angiography. The individuals were divided as being heterozygous for the periodontitis risk haplotype (dominant model, risk haplotype in either chromosome), or without the risk haplotype.3