. 2018 Sep 3;24(7):439–447. doi: 10.1177/1753425918796207

Table 4.

Association between risk haplotype and salivary biomarkers.

	OR (95% CI) for periodontitis risk haplotype, P value
	Model 1^a	Model 2^a	Model 3^a
PLTP (nmol/h/ml)^b	1.194 (0.950–1.502), 0.129	1.195 (0.949–1.505), 0.129	1.197 (0.948–1.512), 0.130
LTA (pg/ml)^b	0.962 (0.880–1.050), 0.383	0.967 (0.884–1.058), 0.467	0.974 (0.890–1.067), 0.572
IL-8 (pg/ml)^b	1.155 (0.878–1.521), 0.303	1.209 (0.907–1.611), 0.195	1.228 (0.919–1.641), 0.165
MPO (ng/ml)^b	1.264 (1.028–1.556), 0.027	1.321 (1.063–1.641), 0.012	1.372 (1.092–1.723), 0.007
CRS^c	1.793 (0.988–3.400), 0.052	1.831 (0.981–3.416), 0.054	1.807 (0.958–3.406), 0.068

Logistic regression model for periodontal risk haplotype in either chromosome (dominant model).

^aModel 1, adjusted for number of teeth; model 2, adjusted additionally for age, gender, diabetes, smoking (never/ever); model 3, adjusted additionally for PPD.

^bOR (95% CI) per unit increase of logarithmically transformed values.

^cOR (95% CI) per change from low risk to moderate/high risk of having periodontitis (CRS II-III vs. I).

CI: confidence interval; CRS: cumulative risk score; LTA: lymphotoxin-α; MPO: myeloperoxidase; OR: odds ratio; PLTP: phospholipid transfer protein.

Significant P values are highlighted in bold. Analyses were performed in the Parogene population (n = 455) including patients with an indication to coronary artery angiography.