Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 10;39(1):122–130. doi: 10.1080/01652176.2019.1655178

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — Receiver operating characteristic curve illustrating the sensitivity and specificity for the use of HMGB1 to distinguish dogs with AP and SIRS from those with AP but no SIRS. The thick diagonal line represents a completely uninformative test, wherein the area under curve is 50%. The area under the curve of the receiver operating characteristic curve represented by the thicker line is 0.82 (95% CI = 0.6462–0.9967). The point of intersection indicates the optimal cut-off of 0.35 ng/mL for the differentiation between AP dogs with and without SIRS, with corresponding sensitivity and specificity of 87.5% (47.35–99.68%) and 71.43% (41.90–91.61%). AP, acute pancreatitis; HMGB1, high mobility group box 1; SIRS, systemic inflammatory response syndrome.