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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Trends Microbiol. 2019 Jun 3;27(9):781–791. doi: 10.1016/j.tim.2019.04.011

Figure 4. Cell wall synthesis distributed by treadmilling FtsZ filaments linked to Ter.

Figure 4.

FtsZ filaments attached to the membrane assemble into the Z ring (FtsZ, FtsA and ZipA colored as in Fig. 2), which consists of patches of FtsZ filaments that move circumferentially around the septum in both directions. Assembly at midcell is aided by the presence of the Ter signal consisting of ZapA bound to FtsZ linked to the MatP macrodomain by ZapB. The septal peptidoglycan synthetic machinery (depicted as a single large complex) consists of enzymes (FtsW-transglcosylase and Ftsl-transpeptidase) and proteins involved in their recruitment (FtsK, FtsQLB) and regulation (FtsQLB, FtsN).