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IGF-1 expression in adipose tissue: adipose tissue sections immuno-stained for IGF-1 with Alexa-Fluor 488 (green). A, NOD mice: IGF-1 is expressed in the adipose tissue of successful transplant recipients euglycemic at 10 mo, but not in failed transplants or controls. B, C57BL/6 mice: IGF-1 is expressed in freshly isolated embryonic BAT but not in adult BAT. BAT, brown adipose tissue; IGF-1, insulin like growth factor 1; NOD, non obese diabetic.
