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. 2019 Oct 8;5(11):e502. doi: 10.1097/TXD.0000000000000944

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Copyright © 2019 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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FIGURE 2. — Perfusion, functional, and biochemical changes during normothermic machine perfusion (NMP). A, Renal blood flow and intra-renal resistance (IRR) during NMP, with a mean arterial pressure maintained between 75–85 mm Hg. B, Left panel—Urine output (UO) per h of NMP for each donor kidney. Right panel—Relationship between UO, creatinine clearance (CrCl), and fractional excretion of sodium (FeNa) in each donor kidney. C, Perfusate acid-base balance (pH, lactate, and bicarbonate) and electrolyte (sodium and osmolality) concentrations over the course of NMP, plotted for each individual kidney. DBD, donation after brain death; DCD, donation after circulatory death.