Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 2;55(6):1313–1323. doi: 10.3892/ijo.2019.4890

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Han et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

NELFE decreased NDRG2 by interacting with its mRNA. (A) Reverse transcription-quantitative PCR results revealed that the mRNA levels of NDRG2 were increased following the knockdown of NELFE. (B) The half-life NDRG2 mRNA increased after NELFE knockdown in PC cells. (C) The decreased NELFE enhanced the luciferase activity of NDRG2 3′untranslated region. (D) RNA immunoprecipitation assays demonstration NELFE directly binding to NDRG2 mRNA. All experiments were repeated three times. ^*P<0.05, ^**P<0.01 vs. NC group. NEFLE, negative elongation factor E; NDRG2, N-Myc elongation factor E; PC, pancreatic cancer.