Table IV.
Enriched KEGG pathway terms for 40 genes downregulated in MDA-MB-231-GHSROS cells.
| KEGG ID | Pathway description | Gene count | BH-FDR | Genes |
|---|---|---|---|---|
| 5310 | Asthma | 3 | 0.00107a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5330 | Allograft rejection | 3 | 0.00107a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5332 | Graft-versus-host disease | 3 | 0.00107a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 4940 | Type I diabetes mellitus | 3 | 0.00111a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 4672 | Intestinal immune network for IgA production | 3 | 0.00119a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5150 | Staphylococcus aureus infection | 3 | 0.00132a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5320 | Autoimmune thyroid disease | 3 | 0.00132a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5416 | Viral myocarditis | 3 | 0.00146a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5321 | Inflammatory bowel disease (IBD) | 3 | 0.00185a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 4612 | Antigen processing and presentation | 3 | 0.00201a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5140 | Leishmaniasis | 3 | 0.00209a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5323 | Rheumatoid arthritis | 3 | 0.00356a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5322 | Systemic lupus erythematosus | 3 | 0.00443a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5145 | Toxoplasmosis | 3 | 0.0069a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 4514 | Cell adhesion molecules | 3 | 0.0114a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 4145 | Phagosome | 3 | 0.0121a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5164 | Influenza A | 3 | 0.0179a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5152 | Tuberculosis | 3 | 0.0181a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5168 | Herpes simplex infection | 3 | 0.0183a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5169 | Epstein-Barr virus infection | 3 | 0.0221a | HLA-DPA1, HLA-DPB1, HLA-DRA |
| 5166 | HTLV-I infection | 3 | 0.0465a | HLA-DPA1, HLA-DPB1, HLA-DRA |
a
KEGG pathway passed the 5% BH-FDR-corrected P-value. BH-FDR, Benjamini-Hochberg false discovery rate; HLA-DPA1, MHC class II, DP α1; HLA-DPB1, MHC class II, DP β1; HLA-DRA, MHC class II, DR α; KEGG, Kyoto Encyclopedia of Genes and Genomes; MHC, major histocompatibility complex.