Table 2.
Detection of CEA+SLeX by PLA analysis and correlation with clinicopathological data.
| PLA signal | |||
|---|---|---|---|
| Neg. | Pos. | P* | |
| Laurén classification | |||
| Intestinal (n=22) | 6 (27.3%) | 16 (72.7%) | 0.942 |
| Diffuse (n=5) | 1 (20.0%) | 4 (80.0%) | |
| Unclassified (n=24) | 6 (25.0%) | 18 (75.0%) | |
| Carneiro classification | |||
| Glandular (n=22) | 6 (27.3%) | 16 (72.7%) | 0.357 |
| Mixed (n=24) | 5 (20.8%) | 19 (79.2%) | |
| Isolated cells (n=4) | 1 (25.0%) | 3 (75.0%) | |
| Solid (n=1) | 1 (100%) | 0 (0.0%) | |
| Ming classification | |||
| Expansive (n=18) | 8 (44.4%) | 10 (55.6%) | 0.063 |
| Infiltrative (n=31) | 5 (16.1%) | 26 (83.9%) | |
| Unclassified (n=2) | 0 (0%) | 2 (100%) | |
| Lymphatic invasion | |||
| Absent (n=12) | 5 (41.7%) | 7 (58.3%) | 0.138 |
| Present (n=39) | 8 (20.5%) | 31 (79.5%) | |
| Venous invasion | |||
| Absent (n=21) | 8 (38.1%) | 13 (61.9%) | 0.081 |
| Present (n=30) | 5 (16.7%) | 25 (83.3%) | |
| pTNM | |||
| I+II (n=30) | 11 (36.7%) | 19 (6.3%) | 0.028 |
| III+IV (n=21) | 2 (9.5%) | 19 (90.5%) | |
| Total | 13 (25.5%) | 38 (74.5%) | |
| Overall Survival | |||
| Average survival (months±SD) | 88.1 ± 13.0 | 60.5 ± 7.8 | 0.168 |
| 95% CI | 62.6 - 113.6 | 45.1 - 75.9 | |