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. 2019 Oct 11;9(24):7417–7430. doi: 10.7150/thno.33470

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This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

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Biodistribution and antitumor efficiency of D-SPB NPs. Biodistribution of DOX in blood (A), tumor (B) and heart (D) of H22 tumor-bearing mice at various time points after i.v. injection; Accumulation of DOX in tumor was calculated as area-under-the-curve (AUC) (C), data is represented as mean ± SD (N = 3); In vivo tumor growth curves (E) and survival number (F) of H22 tumor-bearing mice after eight different treatments, data is represented as mean ± SD (N = 10). (** represents P < 0.01).