Figure 3.
Distribution of FNR648-HSA in tumor-bearing mice. FNR648-HSA was injected into U87MG (Right-thigh) and U87MG-shSPARC (Left-thigh) xenografted tumor-bearing mice. (A) FNR648-HSA images in tumor-bearing mice. The distribution of FNR648-HSA in mice was acquired at various time points after injection. (B) To monitor FNR648-HSA accumulation in tumors, fluorescence signals from tumors were acquired through ROI analyses (n = 3). The image signal unit was total radiant efficacy in [photons/sec]/[μW/cm2].