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. 2019 Mar 1;98(9):e14744. doi: 10.1097/MD.0000000000014744

Figure 2.

Figure 2

The association between NS expression and tumor stage, molecular subtype and P53 status. (A) Representative pictures of immunohistochemical expression of NS in breast cancer samples from early in situ carcinoma and more advanced invasive ductal and lobular carcinoma. (B) GNL3 gene expression and its association with tumor stage in more than 2000 breast cancer samples obtained from Curtis dataset of ONCOMINE database. (C) GNL3 gene expression and its association with breast cancer molecular subtypes classified according to PAM50 in 1881 breast cancer samples obtained from GOBO database. (D) GNL3 gene expression and its association with P53 status in more than 2000 breast cancer samples obtained from Curtis dataset of ONCOMINE database. GOBO = gene expression based outcome, NS = nucleostemin.