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. Author manuscript; available in PMC: 2019 Nov 5.
Published in final edited form as: J Steroid Biochem Mol Biol. 2017 Mar 9;171:157–177. doi: 10.1016/j.jsbmb.2017.03.008

Figure 5.

Figure 5

Substrate binding pocket of 17β-HSD1 with the co-crystallized ligand equilin (PDB 1EQU), catalytic key residues (Ser142 and Tyr155), a flexible loop (residues 188-201) and NADP+.