Table 1.
Patient's immunological investigations.
| Patient value | Normal age-matched value | |
|---|---|---|
| COMPLETE BLOOD COUNT | ||
| Complete blood count | ||
| White blood cell (103/μl) | 10.41 | 6.00–17.00 |
| Red blood cells (106/μl) | 4.27 | 3.60–5.00 |
| Neutrophils (103/μl) | 3.47 | 1.68–8.50 |
| Lymphocytes (103/μl) | 4.38 | 3.6–8.9 |
| Platelets (103/μl) | 371 | 150–450 |
| Hemoglobin (g/dl) | 11 | 10.5–15.5 |
| LYMPHOCYTE SUBSET | ||
| Absolute CD3+ | 2400 | 2,100–6,200 |
| Absolute CD4+ | 184 | 1,300–3,400 |
| Absolute CD8+ | 2012 | 620–2,000 |
| Absolute CD16+CD56+ | 1505 | 720–2,600 |
| Absolute CD19+ cells/mL | 283 | 720–2,600 |
| CD19+CD24+CD38+ cells/mL (Transitional B) | 18 | 56–101 |
| CD19+CD24-CD38+ cells/mL (Plasma cells) | 70 | 40–55 |
| CD3+CD4+CD27+CD45RA+% (naÏve) | 0.3 | 63–91 |
| CD3+CD4+CD27+CD45RA-% (CM) | 66.3 | 10–26 |
| CD3+CD4+CD27-CD45RA-% (EM) | 33.4 | 3–16 |
| CD3+CD4+C27-CD45RA+% (TEMRA) | 0.1 | 3–12 |
| CD3+CD4+CD31+CD45RA+% (RTE) | 0.2 | >40 |
| CD3+CD8+CCR7+CD45RA+ % (naÏve) | 0.07 | 71–98 |
| CD3+CD8+CCR7+CD45RA-% (CM) | 0.24 | 3–15 |
| CD3+CD8+CCR7-CD45RA-% (EM) | 97.9 | 9–47 |
| CD3+CD8+CCR7-CD45RA+% (TEMRA) | 1.7 | 7–25 |
| CD3+ TCR alpha-beta | 96 | 26–100 |
| CD3+ TCR gamma-delta | 3.6 | 1–13 |
| LYMPHOCYTE STIMULATION TO MITOGENS (cpm) | ||
| Phytohemagglutinin | 2.788 | >35.000 |
| OKT3 | 4.838 | >25.000 |
| SERUM IMMUNOGLOBULIN LEVELS | ||
| IgG (mg/dL) | 3,603 | 264–1,509 |
| IgA (mg/dL) | 680 | 17–178 |
| IgM (mg/dL) | 509 | 48–337 |
| IgE (IU/mL) | 2.9 | <2 |
| ANTIBODY RESPONSE TO VACCINATIONS | ||
| Tetanus titer (IU/mL) | 0.13 | >0.1 |
| Haemophilus titer (mg/l) | 0.2 | >0.1 |
| Post-pneumococcal titer (mg/l) | <3 | >35 |
CM, central memory; EM, effector memory; TEMRA, terminally differentiated effector memory; RTE, recent thymic emigrants.