Table 1.
Baseline characteristics
| Total | n (%)/median (IQR) |
|---|---|
| n = 1013 | |
| Gender | |
| Male | 540 (54.5) |
| Female | 450 (45.5) |
| Age, years | 59 (50–67) |
| BMI | 25.4 (22.6–28.2) |
| Preoperative jaundice | 90 (8.9) |
| ASA class | |
| I | 103 (11.0) |
| II | 489 (52.0) |
| III | 280 (29.8) |
| IV | 68 (7.2) |
| Period of treatment | |
| 1990–2000 | 35 (3.5) |
| 2001–2005 | 116 (11.5) |
| 2006–2010 | 411 (40.6) |
| 2011–2017 | 451 (44.5) |
| Preoperative chemotherapy | 55 (5.4) |
| Major resection | 593 (58.9) |
| Size, cm | 6.2 (4.3–9.0) |
| Major vascular invasion | 100 (10.0) |
| Microvascular invasion | 254 (25.7) |
| Perineural invasion | 149 (16.3) |
| Extension into adjacent organs | 77 (7.7) |
| R1 resection | 128 (12.8) |
| Lymph node metastases | 175 (17.3) |
| Multiple lesions | |
| Median number of tumors | 2 (2–3) |
| 2 lesions | 107 (10.7) |
| > 2 lesions | 78 (7.8) |
| Oligometastases | |
| Lung | 2 (0.2) |
| Peritoneum | 11 (1.1) |
| Distant lymph nodes | 9 (0.9) |
| Other | 5 (0.5) |