Table 2.
Postoperative outcomes stratified by intrahepatic metastases
| Variable | Single tumor (n = 821) | Multiple tumors (n = 185) | p value* |
|---|---|---|---|
| Preoperative chemotherapy | 40 (4.9) | 15 (8.1) | 0.080 |
| R1 margin | 97 (11.9) | 29 (15.8) | 0.154 |
| Lymph node metastases | 127 (15.5) | 47 (25.4) | 0.001 |
| Oligometastases | 20 (2.4) | 7 (3.8) | 0.314 |
| Direct invasion other organ | 48 (5.9) | 29 (15.8) | < 0.001 |
| Perineural invasion | 118 (15.9) | 30 (18.0) | 0.505 |
| Major vascular invasion | 76 (9.3) | 23 (12.5) | 0.189 |
| Major resection | 458 (55.9) | 131 (72.4) | < 0.001 |
| Postoperative complication | 343 (41.8) | 92 (49.7) | 0.049 |
| Clavien–Dindo grade | 0.036 | ||
| I-II | 207 (60.0) | 44 (47.8) | |
| IIIa-V | 138 (40.0) | 48 (52.2) | |
| 90-day postoperative mortality | 50 (6.1) | 11 (5.9) | 0.941 |
| Length of stay, days | 12 (7–17) | 12 (7–18) | 0.668 |
| Recurrence | 430 (52.4) | 137 (74.1) | < 0.001 |
*Fisher’s exact test was used for categorical variables with expected counts < 5