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. 2019 Nov 5;9:16040. doi: 10.1038/s41598-019-52572-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Overview of the function of the secreted proteins. Proteins were classified manually based on BLAST similarity and GO annotation to gain an overview of their biological function. Proteins with a hydrolysing activity are the largest group; in total 27 proteases, 8 carbohydrate/peptidoglycan degrading as well as 13 lipid degrading/binding proteins were identified. 66 proteins have similarities to predicted or uncharacterized proteins, while 41 proteins do not have any similarities to known proteins.