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. 2019 Nov 5;9:16064. doi: 10.1038/s41598-019-52352-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Distal proximal skin temperature gradient (DPG) 15-minute means ± SEM per session over time. (b) The change in DPG during the exposure period (L6-L3) and till the end of the experiment (L9-L3). (c) Underarm-Finger gradient 15-minute means ± SEM per session over time. (d) The change in underarm-finger gradient during exposure period (L6-L3) and till the end of the experiment (L9-L3). The grey dotted area (T ≦ 60) indicates the prior light exposure and the diagonally hatched area indicates the timing of the light exposure period (a,c). Statistically significant differences between sessions and between 1-hour means are indicated: ^#p < 0.10, *p < 0.05 and **p < 0.01.