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. 2019 Nov 5;9:16014. doi: 10.1038/s41598-019-52408-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Involvement of ubiquitin binding by p62 in Tax-induced NF-κB activation: working model. p62 associates with Tax in peri-golgian structures, downstream of the formation of Tax/IKK complexes, and participates in the efficient activation of the IKK complex by a mechanism requiring binding to ubiquitin chains. See text for further details. T1BP1: TAX1BP1. Artwork is a derivative of Servier Medical Art (https://smart.servier.com/), used under CC BY 3.0 FR (https://creativecommons.org/licenses/by/3.0/), and includes modifications in shapes, colors and disposition of the original material.